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DENTINOGENESIS GHOST CELL TUMOUR WITH ODONTOMA: A CASE REPORT

Chandraseharan P, Sharif JM, Sockalingam G

Introduction: Dentinogenic Ghost Cell Tumour (DGCT) is defined by WHO as a locally
invasive neoplasm. DGCT presents as intraosseous and less commonly as an extraosseous
variant, with highest prevalence in the second and seventh decades. It occurs equally in
the maxilla and mandible with slight male predilection. Case report: A 10-year-old female,
first presented to Hospital Kuala Lipis with a painless, slow growing swelling at the left
mandibular region in four months prior. Aspiration, incisional biopsy and marsupialization
were performed and its histopathological examination revealed as a calcifying cystic
odontogenic tumour. Upon four months review, swelling appeared bigger and
subsequently was referred to our department for further management. Clinical
examination showed facial asymmetry with soft tissue swelling distal to tooth 31 to 36 with
bucco-lingual expansion. Radiographic examinations revealed a well-defined unilocular
radiolucency with areas of radiopacity at left mandibular area displacing teeth 33, 34 and
35. Enucleation, peripheral ostectomy and chemical curettage were performed under
general anaesthesia and resulting defect was packed with ribbon gauze impregnated with
iodoform paste and changed on a monthly basis. Histopathological examination revealed
dentinogenic ghost cell tumour with odontoma. DGCT has high recurrence rate, thus, an
enucleation with adequate curettage of underlying bone is recommended. Conclusion: The
present case emphasizing the marsupialization as an option; however, immediate
enucleation should be considered due to its local invasive nature of the tumor.
Conservative management is recommended in the pediatric age group. Regular follow-up
is mandatory for better prognosis and to detect any recurrence for immediate intervention.

Presented at the 5 MAPD Biennial Scientific Conference & Trade Exhibiton on 13 April 2019
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Dr Prasanna Chandraseharan
Dr Ganasalingam A/L Sockalingam
Department of Paediatric Dentistry
Hospital Tunku Azizah
Kuala Lumpur

Dr Jama’iah Mohd Shariff
Dental Centre
Sunway Medical Centre Sdn. Bhd
Selangor Malaysia

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