Page 91 - FINAL COMPENDIUM 2020-2021 27.2.2022

PATTERN OF ANTIBIOTIC PROPHYLAXIS PRACTICE FOR DENTAL PROCEDURES IN
CHILDREN WITH CONGENITAL HEART DISEASE

Sharif JM, Raja Shahardin RZ, Sockalingam G

Introduction: Various antibiotic prophylaxis guidelines have been published such as the
American Heart Association 2007, British Society for Antimicrobial Chemotherapy 2006,
National Institute for Health and Clinical Excellence 2008, European Society of Cardiology
2015, and in Malaysia, the National Antibiotic Guideline 2014 and Clinical Practice
Guidelines for the Prevention, Diagnosis and Management of Infective Endocarditis 2017.
Objective: To determine the pattern of antibiotic prophylaxis practice for dental
procedure in children with congenital heart disease (CHD) at the Department of Paediatric
Dentistry, Kuala Lumpur Hospital. Materials and methods: A retrospective study of dental
records from 2010 to 2015 was done by collecting data on the source and reason of
referral, types of heart condition, dental procedure, and antibiotic given. Results: There
were 210 patients; 69.5% had acyanotic CHD, 21.9% cyanotic CHD, 6.7% repaired CHD
with residual defects, and 1.9% with previous infective endocarditis. Slightly more than
58% were referred from government doctors (paediatric cardiologist and National Heart
Institute). The common cause for referral was dental assessment (47.6%). Antibiotics
were prescribed to 23.3% (49/210) patients, of which, 34.7% was given ampicillin or
amoxicillin/clavulanic acid. About 96% of cyanotic heart cases undergoing invasive dental
procedures were prescribed antibiotic prophylaxis. Almost 31% were prescribed with
antibiotic prophylaxis even though it was not indicated. Conclusion: This study shows that
there is variability in prescribing antibiotic prophylaxis, and it is important for dental
clinicians to standardize the practice of giving antibiotic prophylaxis.

Publised in Indian Soc Pedod Prev Dent. 2020 Apr-Jun;38(2):126-131. doi: 10.4103/JISPPD.JISPPD_235_18. PMID: 32611857

Dr Jama’iah Mohd Shariff
Dental Centre
Sunway Medical Centre Sdn. Bhd
Selangor, Malaysia.

Dr Raja Zarina Raja Shahardin
Dr Ganasalingam A/L Sockalingam
Department of Paediatric Dentistry
Hospital Tunku Azizah
Kuala Lumpur

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