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PERIODONTAL MANAGEMENT IN A PRIMARY POLYCYTHEMIA RUBRA VERA PATIENT: A
CASE REPORT

Farah WH, Nurulhuda M

Introduction: Polycythemia rubra vera (PRV) is a myeloproliferative disease, which is
characterized by the proliferation of all three major haematopoietic groups (erythrocytes,
leucocytes and platelets). This haematological condition presented with different clinical
manifestations depending on the thrombo-hemorrhagic status of the patient. It is
suggested patient with pre-existing PRV may suffer complication during periodontal
treatment. Thus, this case would therefore demonstrate periodontal management
outcome in PRV patient. Case report: A 60-year-old Malay gentleman presented in
Periodontal Clinic, University Kebangsaan Malaysia. He was a known case of primary PRV
for the past 5 years. Intraoral examination showed generalized periodontal deep pockets
ranging from 5 to 10 mm. He was diagnosed as Stage III Grade C periodontitis. Non-surgical
periodontal therapy was provided, followed by surgical correction of residual periodontal
deep pockets on teeth 17, 11 and 23. He was reviewed at 4-month intervals for supportive
periodontal therapy after stabilization of his periodontal condition. Conclusion:
Polycythemia rubra vera (PRV) patients should have preoperative therapeutic control for
more than 4 months and treatment with myelosuppressive agents prior to periodontal
surgery. Good oral hygiene and periodical supportive periodontal therapy are the key
factors for successful periodontal treatment outcomes in well-controlled PRV patients.

Published in Spec Care Dentistry. 2021 Jan;41(1):92-97. doi: 10.1111/scd.12537.
th
Presented at the 13 International Meeting of the Asian Pacific Society. September 28-29, 2019.
Dr Farah Wahida Hassan
Peringgit Melaka Dental Clinic
Ministry of Health
Melaka

Dr Nurulhuda Mohd
Periodontic Unit
Department of Restorative Dentistry
Faculty of Dentistry
Universiti Kebangsaan Malaysia
Malaysia

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