Page 83 - 7. FINAL draft Compendium 2019 2020_22072022

PATTERN OF ANTIBIOTIC PROPHYLAXIS PRACTICE FOR DENTAL PROCEDURES IN
CHILDREN WITH CONGENITAL HEART DISEASE
NMRR ID: 310707

Sharif JM, Raja Shahardin RZ, Sockalingam G

Introduction: Various antibiotic prophylaxis guidelines have been published such as the
American Heart Association 2007, British Society for Antimicrobial Chemotherapy 2006,
National Institute for Health and Clinical Excellence 2008, European Society of Cardiology
2015, and in Malaysia, the National Antibiotic Guideline 2014 and Clinical Practice
Guidelines for the Prevention, Diagnosis and Management of Infective Endocarditis 2017.
Objective: The aim of the study is to determine the pattern of antibiotic prophylaxis
practice for dental procedure in children with congenital heart disease (CHD) at the
Department of Paediatric Dentistry, Kuala Lumpur Hospital. Materials and Method: A
comparative cross-sectional study of dental records from 2010 to 2015 was done by
collecting data on the source and reason of referral, types of heart condition, dental
procedure, and antibiotic given. Results: There were 210 patients; 69.5% had acyanotic
CHD, 21.9% cyanotic CHD, 6.7% repaired CHD with residual defects, and 1.9% with previous
infective endocarditis. Slightly more than 58% were referred from government doctors
(pediatric cardiologist and National Heart Institute). The common cause for referral was
dental assessment (47.6%). Antibiotics were prescribed to 23.3% (49/210) patients, of
which, 34.7% was given ampicillin or amoxicillin/clavulanic acid. About 96% of cyanotic
heart cases undergoing invasive dental procedures were prescribed antibiotic prophylaxis.
Almost 31% were prescribed with antibiotic prophylaxis even though it was not indicated.
Conclusion: This study shows that there is variability in prescribing antibiotic prophylaxis,
and it is important for dental clinicians to standardize the practice of giving antibiotic

prophylaxis.
Published in Indian Soc Pedod Prev Dent. 2020 Apr-Jun;38(2):126-131. doi: 10.4103/JISPPD.JISPPD_235_18. PMID:
32611857.
Dr Jama’iah Mohd Shariff
Dental Centre
Sunway Medical Centre Sdn. Bhd
Selangor Malaysia

Dr Raja Zarina Raja Shahardin
Dr Ganasalingam A/L Sockalingam
Department of Paediatric Dentistry
Tunku Azizah Hospital
Kuala Lumpur

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