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PERIODONTAL MANAGEMENT IN A PRIMARY POLYCYTHEMIA RUBRA VERA PATIENT: A
CASE REPORT
Farah Wahida H, Nurulhuda M
Introduction: Polycythemia rubra vera (PRV) is a myeloproliferative disease, which is
characterized by the proliferation of all three major hematopoietic groups (erythrocytes,
leucocytes and platelets). This haematological condition presented with different clinical
manifestations depending on the thrombohaemorrhagic status of the patient. It is
suggested patient with pre-existing PRV may suffer complication during periodontal
treatment. Thus, this case would therefore demonstrate periodontal management
outcome in PRV patient. Case report: A 60-year-old Malay gentleman presented to the
Periodontic Clinic, Universiti Kebangsaan Malaysia. He was a known case of primary PRV
for the past 5 years. Intraoral examination showed generalized periodontal deep pockets
ranging from 5 to 10 mm. He was diagnosed as Stage III Grade C periodontitis. Nonsurgical
periodontal therapy was provided, followed by surgical correction of residual periodontal
deep pockets on teeth 17, 11, and 23. He was reviewed at 4-month intervals for
supportive periodontal therapy after stabilization of his periodontal condition.
Conclusions: Polycythemia rubra vera (PRV) patients should have preoperative
therapeutic control for more than 4 months and have been treated with
myelosuppressive agents prior to periodontal surgery. Good oral hygiene and periodical
supportive periodontal therapy are the key factors for successful periodontal treatment
outcomes in well-controlled PRV patients.
Keywords: Periodontics, Polycythemia rubra vera
Published in Hassan FW, Mohd N. Periodontal management in a primary polycythemia rubra vera patient: A case report.
Spec Care Dentist. 2021 Jan;41(1):92-97. doi: 10.1111/scd.12537. Epub 2020 Oct 30. PMID: 33125720
Presented at 13 Asian Pacific Society Periodontal Meeting on 28 – 29 September 2019
th
Dr Farah Wahida Hassan
Periodontic Specialist Unit
Rembia Dental Clinic
Alor Gajah, Melaka
Dr Nurulhuda Mohd
Faculty of Dentistry
Universiti Kebangsan Malaysia
Kuala Lumpur
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