Page 165 - FINAL COMPENDIUM 2020-2021 27.2.2022

EFFECTIVENESS OF RESIN INFILTRATION IN CARIES INHIBITION AND AESTHETIC
APPEARANCE IMPROVEMENT OF WHITE-SPOT LESIONS: AN UMBRELLA REVIEW

Lin GSS, Chan DZK, Low TT, Lee HY, Laer TS, Pillai MPM, Yew YQ, Wafa SWWSST
Objectives: Resin infiltration technique is a minimal interventive approach to manage
white-spot lesions. The present umbrella review aimed to comprehensively appraise the
previously published systematic reviews on the effectiveness of resin infiltration in
arresting caries progression and improving the aesthetic appearance of white-spot
lesions. Material and methods: Ten electronic databases were searched between January
1960 and May 2021. Only systematic reviews published in English on the use of resin
infiltration in primary or permanent teeth were included. The degree of overlap across
each review was calculated using the Corrected Covered Areas (CCA) method and their
evidence quality were assessed using AMSTAR 2 assessment tool. Umbrella meta-analysis
was carried out using a random-effects model. Results: Thirteen systematic reviews were
chosen, but only eight were eligible for an umbrella meta-analysis. The overall CCA value
was very high (19.8%), whereas only three studies were classified as ‘High Quality’.
Qualitative synthesis suggested that resin infiltration demonstrated acceptable aesthetic
results, whereas quantitative analysis showed favourable outcomes in minimizing the risk
of caries progression (RR: 0.32; 95 % CI: 0.29 to 0.36). White-spot lesions treated with
resin infiltrant in permanent teeth demonstrated a lower risk of caries progression
(P<0.001) than primary teeth. Overall, low data heterogeneity was observed (I2: 0% to
20%). However, quantitative umbrella analysis on the aesthetic outcome was unable to
perform due to limited data. Conclusion: Resin infiltration can be regarded as an effective
treatment modality in minimizing the risk of caries progression and improving the
aesthetic appearance of white-spot lesions. Future well-designed high-quality systematic
reviews with long-term follow-up and more control of confounding variables are
warranted.

Keywords: Conservative treatment, Dental caries, Dental resins, Evidence-based dentistry,
Umbrella review

J Evid Based Dent. 2022 (Article in-press)
nd
Poster presentation at the 2 University of Malaya – China Medical University Joint Postgraduate Research Symposium on
25 November 2021
Galvin Sim Siang Lin Hern Yue Lee
Department of Dental Materials Seberang Jaya Dental Clinic
Faculty of Dentistry Ministry of Health Malaysia
Asian Institute of Medicine, Science and Technology Butterworth, Penang, Malaysia
(AIMST) University
Bedong, Kedah, Malaysia Ting Ting Low
Gunung Rapat Dental Clinic
Daryl Zhun Kit Chan Ministry of Health Malaysia
Yan Dental Clinic Ipoh, Perak, Malaysia
Ministry of Health Malaysia
Yan, Kedah, Malaysia

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