Page 104 - FINAL COMPENDIUM 2020-2021 27.2.2022

MAXILLARY AND MANDIBULAR OSTEOMYELITIS ASSOCIATED WITH OSTEOPETROSIS: A
CASE REPORT

Eunice CL, Leong KJ, Azalina O, Goh DS, Nurnabiha MJ
Introduction: Osteopetrosis also known as marble bone disease, is a rare hereditary bone
disorder characterized by the malfunction of osteoclast and impairment of bone
resorption resulting in bones hardening and abnormal bone growth. The typical finding
on the x-ray is the increased opacity of the bones. Complications such as osteomyelitis
are often difficult to treat and can be life-threatening. Case report: A 3-year-old boy, born
of consanguineous marriage, was referred to the Department of Paediatric Dental
Surgery, with concerns about his missing and abnormal-looking tooth. Apart from being
diagnosed with a learning disability, he was investigated for bilateral eye retinal
dystrophia. On examination, he presented with hypodontia and multiple grossly carious
teeth. Total extraction was later performed under general anaesthesia. Intraoperatively,
his teeth were noted to be hypomineralised with abnormal morphology. Postoperative
reviews showed poor wound healing of the sockets with exposed alveolar bone on both
upper and lower jaws. The child was treated with multiple courses of antibiotics and was
referred to the Department of Paediatrics for further investigation. He was later
diagnosed with osteopetrosis following an episode of admission due to severe anaemia
and pneumonia, after a chest x-ray was taken as part of the investigation. His oral
condition continued to deteriorate further and required multiple courses of antibiotics
and repeated debridement of necrotic bone. Unfortunately, the primary closure of the
bony defect failed and he is currently on long-term follow-up for oral wound care along
with long-term antibiotics.

Keywords: Osteopetrosis, Paediatric.
Oral presentation at the Malaysian International Dental Exhibition and Conference (MIDEC) 2021 on 31July 2021

Dr Eunice Chong Li-Ern
Dr Leong Kei Joe
Dr Goh Dai Shan
Dr Nurnabiha binti Mohd Jabid
Department of Paediatric Dentistry
Sabah Women and Children Hospital
Kota Kinabalu, Sabah

Dr Azalina binti Osman
Department of Paediatric Dentistry
Queen Elizabeth Hospital
Kota Kinabalu, Sabah

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